Antimicrobial Resistance Profiles of Multidrug-Resistant Pathogens in a Military Hospital: A Three-Year Study

This study investigated multidrug-resistant (MDR) microorganisms at the 424 General Military Training Hospital in Thessaloniki, Greece, from 2021–2023. Of 7,856 isolates, 131 were MDR, mainly Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa. K. pneumoniae showed rising resistance to carbapenems and cephalosporins, A. baumannii remained highly resistant, and P. aeruginosa displayed moderate resistance. MDR pathogens were most often found in urine and blood (dominated by K. pneumoniae), respiratory samples (A. baumannii), and wound cultures (P. aeruginosa). The ICU and emergency department were key hotspots. The findings highlight the need for stronger stewardship, infection control, and ongoing surveillance to curb MDR infections.